Manoel Luis Pereira da Silva Costa

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Ciências Biomédicas

Departamento:

Docentes/ICB

ORCID:

não disponível no Lattes


Formação:
  • University of Pennsylvania

    | Pós-Doutorado | 2001 - 2001
  • Woods Hole Marine Biological Laboratories

    Optical Microscopy & Imaging Biological Sciences | Especialização | 1991 - 1991
  • Instituto Oswaldo Cruz Fiocruz

    | Pós-Doutorado | 1991 - 1993
  • University of Pennsylvania

    Cell Biology | Especialização | 1989 - 1991
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1987 - 1991
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Mestrado | 1983 - 1986
  • Universidade Federal do Rio de Janeiro

    Biologia Modalidade Genética | Graduação | 1979 - 1982
Laboratórios:
Nuvens de Palavras:
Artigos:

(84.06% artigos com DOI)

Titulo DOI Ano
Improving quantification of myotube width and nuclear/cytoplasmic ratio in myogenesis research 10.1016/j.cmpb.2023.107354 2023
Blood meal digestion and changes in lipid reserves are associated with the post-ecdysis development of the flight muscle and ovary in young adults of Rhodnius prolixus 10.1016/j.jinsphys.2023.104492 2023
Evaluating the dissemination of evolutionary biology concepts in medicine 10.1590/1414-431x2023e13052 2023
Manganese Exposure Induces Cellular Aggregates and the Accumulation of β-Catenin in Skin of Zebrafish Embryos 10.1089/zeb.2022.0056 2023
What does desmin do: A bibliometric assessment of the functions of the muscle intermediate filament 10.1177/15353702221075035 2022
Simvastatin and Muscle: Zebrafish and Chicken Show that the Benefits are not Worth the Damage 10.3389/fcell.2022.778901. eCollection 2022 2022
Epithelial-to-mesenchymal transition as a learning paradigm of cell biology 10.1002/cbin.11967 2022
A comparative study on the use of microscopy in pharmacology and cell biology research 10.1371/journal.pone.0245795 2021
The Role of Embryonic Chick Muscle Cell Culture in the Study of Skeletal Myogenesis 10.3389/fphys.2021.668600 2021
Activation of YAP regulates muscle fiber size in a PKC-dependent mechanism during chick in vitro myogenesis 10.1007/s10974-021-09608-8 2021
Do Medicine and Cell Biology talk to each other? A study of vocabulary similarities between fields 10.1590/1414-431X2021e11728 2021
The perinuclear region concentrates disordered proteins with predicted phase separation distributed in a 3D network of cytoskeletal filaments and organelles 10.1016/j.bbamcr.2021.119161 2021
Comparative study of calcium and calcium-related enzymes with differentiation markers in different ages and muscle types in mdx mice Histology and Histopathology 10.14670/HH-18-145 2020
Acidic compartments size, positioning and function during myogenesis and their modulation by the Wnt/beta-catenin pathway 10.1155/2020/6404230 2020
The scaffolding protein calpain-3 has multiple distributions in embryonic chick muscle cells and it is essential for the formation of muscle fibers 10.1016/j.tice.2020.101436 2020
Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice 10.1038/s41598-019-38609-4 2019
Isoproterenol induces an increase in muscle fiber size by the proliferation of Pax7¿positive cells and in a mTOR¿independent mechanism 10.1002/cbin.11190 2019
Distinct interactions between epithelial and mesenchymal cells control cell morphology and collective migration during sponge epithelial to mesenchymal transition 10.1002/jmor.21090 2019
γ-Secretase Inhibition Induces Muscle Hypertrophy in a Notch-Independent Mechanism 10.1002/pmic.201700423 2018
Sonic Hedgehog signaling and Gli-1 during embryonic chick myogenesis 10.1016/j.bbrc.2018.11.071 2018
Analysis of undergraduate cell biology contents in Brazilian public universities 10.1002/cbin.10720 2017
Flotillins control zebrafish epiboly through their role in cadherin-mediated cell-cell adhesion 10.1111/boc.201700001 2017
Cellular migration, transition and interaction during regeneration of the sponge Hymeniacidon heliophila 10.1371/journal.pone.0178350 2017
Knockdown of Lmo7 inhibits chick myogenesis 10.1002/1873-3468.12067 2016
Membrane cholesterol depletion reduces breast tumor cell migration by a mechanism that involves non-canonical Wnt signaling and IL-10 secretion 10.1186/s41231-016-0002-4 2016
Distinctive Effects of Cytochalasin B in Chick Primary Myoblasts and Fibroblasts 10.1371/journal.pone.0154109 2016
Alterations in zebrafish development induced by simvastatin: Comprehensive morphological and physiological study, focusing on muscle 10.1177/1535370216659944 2016
The Role of Na+/K+-ATPase during Chick Skeletal Myogenesis 10.1371/journal.pone.0120940 2015
Structural Analysis of Alterations in Zebrafish Muscle Differentiation Induced by Simvastatin and their Recovery with Cholesterol 10.1369/0022155415580396 2015
Cytoskeleton and Adhesion in Myogenesis 10.1155/2014/713631 2014
Cholesterol depletion induces transcriptional changes during skeletal muscle differentiation 10.1186/1471-2164-15-544 2014
Toxicological in vitro and subchronic evaluation of LASSBio-596 10.1016/j.fct.2014.07.037 2014
Differences in the Expression and Distribution of Flotillin-2 in Chick, Mice and Human Muscle Cells 10.1371/journal.pone.0103990 2014
Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells 10.1371/journal.pone.0063177 2013
Induction Of Skeletal Muscle Differentiation In Vitro By Therapeutic Ultrasound 10.1016/j.ultrasmedbio.2013.10.013 2013
Reentrant spiral waves of spreading depression cause macular degeneration in hypoglycemic chicken retina 10.1073/pnas.1121111109 2012
2D and 3D-Organized Cardiac Cells Shows Differences in Cellular Morphology, Adhesion Junctions, Presence of Myofibrils and Protein Expression 10.1371/journal.pone.0038147 2012
Cholesterol depletion by methyl-β-cyclodextrin enhances cell proliferation and increases the number of desmin-positive cells in myoblast cultures 10.1016/j.ejphar.2012.07.035 2012
α-Cyclodextrin enhances myoblast fusion and muscle differentiation by the release of IL-4 10.1016/j.cyto.2011.04.018 2011
Membrane Cholesterol Depletion by Methyl-?-Cyclodextrin Enhances the Expression of Cardiac Differentiation Markers 10.1159/000316005 2010
Distribution of cytoskeletal and adhesion proteins in adult zebrafish skeletal muscle 2009
Cell adhesion in zebrafish myogenesis: Distribution of intermediate filaments, microfilaments, intracellular adhesion structures and extracellular matrix 10.1002/cm.20301 2008
Wnt/?-catenin pathway activation and myogenic differentiation are induced by cholesterol depletion 10.1111/j.1432-0436.2006.00129.x 2007
Chondroitin sulfate and keratan sulfate are the major glycosaminoglycans present in the adult zebrafish Danio rerio (Chordata-Cyprinidae) 10.1007/s10719-007-9046-z 2007
A soluble and active form of Wnt-3a protein is involved in myogenic differentiation after cholesterol depletion 10.1016/j.febslet.2007.11.047 2007
Desmin filaments are stably associated with the outer nuclear surface in chick myoblasts 10.1007/s00441-005-0063-6 2006
Association between the muscle-specific proteins desmin and caveolin-3 in muscle cells 10.1007/s00441-006-0296-z 2006
Cholesterol depletion by methyl-?-cyclodextrin enhances myoblast fusion and induces the formation of myotubes with disorganized nuclei 10.1007/s00441-004-1004-5 2005
Changes in cell shape and desmin intermediate filament distribution are associated with down-regulation of desmin expression in C2C12 myoblasts grown in the absence of extracellular Ca2+ 10.1590/S0100-879X2005000700005 2005
Desmin: molecular interactions and putative functions of the muscle intermediate filament protein 10.1590/S0100-879X2004001200007 2004
Cytoskeletal and cellular adhesion proteins in zebrafish (Danio rerio) myogenesis 10.1590/S0100-879X2003000800019 2003
Changes in cell shape, cytoskeletal proteins and adhesion sites of cultured cells after extracellular Ca2+ chelation 10.1590/S0100-879X2003000800018 2003
Some distinctive features of zebrafish myogenesis based on unexpected distributions of the muscle cytoskeletal proteins actin, myosin, desmin, ?-actinin, troponin and titin 10.1016/S0925-4773(02)00149-1 2002
Volumetric quantification of the gastric emptying: computer-based method for generation of volumetric index from fluoroscopic images 10.1016/S0169-2607(00)00123-1 2001
Intermediate filaments modulation in an in vitro model of the hepatic stellate cell activation or conversion into the lipocyte phenotype 10.1139/bcb-79-4-409 2001
Induction of the lipocyte phenotype in murine hepatic stellate cells: reorganisation of the actin cytoskeleton 10.1007/s004410100428 2001
The cytoskeleton of the electric tissue of Electrophorus electricus, L. 10.1590/S0001-37652000000300008 2000
Avaliação qualitativa e quantitativa do esvaziamento gástrico através do método videofluoroscópico 2000
Videofluoroscopia como método de avaliação do esvaziamento gástrico 2000
Distribution of F-actin, ?-actinin, tropomyosin, tubulin and organelles in by immunofluorescence microscopy 10.1016/S0040-8166(98)80035-9 1998
Differences In The Isodesmin Pattern Between The Electric Organs Of The Electrophorus Electricus, L 1998
Intermediate filament proteins in TPA-treated skeletal muscle cells in culture 10.1007/bf00124242 1996
Myofibrillar Breakdown And Cytoskeletal Alterations In Heart Muscle Cells During Invasion By Trypanosoma Cruzi: Imunological And Ultra- Structural Study 1993
Myod Converts Primary Dermal Fibroblasts, Chondroblasts, Smooth Muscleand Retinal Pigmented Epithelial Cells Into Striated Mononucleated Myoblasts And Multinucleated Myotubes 1990
Autonomous Expression Of The Differentiation Program Of Cells In The Cardiac And Skeletal Myogenic Lineages 1990
Desmin Expression In The Electric Organs Of Electrophorus Electricus, L. 1988
Desmin Heterogeneity In The Main Organ Electrophorus Electricus, L. 1988
Caracterisation de La Desmine Dans L`Organe Electrique de L`Electro- Phorus Electricus, L. 1986
The Purification And Characterization Of Desmin In The Electrophorus Elctricus, L. 1985
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Three-dimensional Studies of Myogenesis: the Zebrafish Model 2010
Three-dimensional Studies of Myogenesis: Cardiac Cells Culture Model 2010
Cytoskeletal And Adhesion Proteins In The Zebrafish (Danio Rerio) Myogenesis 2008
Estudo das distribuições de caveolina-3 e de desmina ao longo da diferenciação muscular esquelética 2005
Identificação bioquímica das isoformas de proteínas do citoesqueleto de músculo cricofaríngeo humano 2005
Análise Bioquímica de Proteínas do Citoesqueleto de Peixe-zebra (Danio rerio) 2004
Proteínas de Adesão na Miogênese do Peixe-Zebra (Danio rerio) 2004
Cytoskeletal and adhesion proteins in the zebrafish (Danio rerio) myogenesis. 2004
Envolvimento de rafts na fusão de células de músculo esquelético 2004
Efeitos da retirada de colesterol na diferenciação do músculo esquelético 2004
Rafts and cholesterol are involved in skeletal muscle differentiation 2004
Estudo do envolvimento do colesterol na fusão de células de músculo esquelético 2003
Heparin improve the muscle regeneration after damage by snake venom 2003
Cytoskeletal and Adhesion Proteins in the Zebrafish (Danio rerio) Myogenesis 2003
HEPARIN IMPROVES MOUSE MUSCLE REGENERATION AFTER BEING DAMAGED BY BOTHROPS JARARACUSSU VENOM 2003
Rafts and cholesterol are involved in skeletal muscle differentiation 2003
Rafts e colesterol estão envolvidos na diferenciação do músculo esquelético 2003
Estudo de Proteínas do Complexo de Adesão Focal em Peixe-Zebra (Danio rerio). 2002
Estudo do Envolvimento do Colesterol na Fusão de Células de Músculo Estudo do Envolvimento do Colesterol na Fusão de Células de Músculo Esquelético de Galinha Crescidas em Cultura 2002
Distinctive long-term effects of cytochalasin B in cytoskeletal proteins in chick primary myoblasts and fibroblasts 2002
Cytoskeletal proteins in the zebrafish (Danio rerio) myogenesis. 2002
Extracellular Ca2+ regulates cell shape, microfilaments and microtubules distribution and adhesion plaques clustering in cultured cells 2002
Extracellular Ca regulates cell shape, microfilaments and microtubules distribution and adhesion plaques clustering in cultured cells 2002
Cytoskeletal proteins in the zebrafish (Danio rerio) myogenesis 2002
Regulação da forma celular e da organização de microfilamentos e de placas de adesão por cálcio extra-celular 2002
Estudo do envolvimento do colesterol na fusão de células de músculo esquelético de galinha crescidas em cultura 2002
Estudo de proteínas do complexo de adesão focal em peixe-zebra (Danio rerio) 2002
Effects of EGTA in skeletal muscle cells grown in culture 2001
Cytoskeletal proteins in the zebrafish (Danio rerio) muscle development. 2001
Muscle cytoskeletal proteins in the zebrafish (Danio rerio) development. 2001
Mudanças na forma celular e na organização de proteínas do citoesqueleto em mioblastos da linhagem celular C2C12 crescidos em meio sem cálcio 2001
Muscle cytoskeletal proteins in the zebrafish (Danio rerio) development 2001
Cytoskeletal proteins in the zebrafish (Danio rerio) muscle development 2001
Efeitos do quelante de cálcio EGTA sobre a forma celular e o citoesqueleto de células musculares e de fibroblastos 2001
Cytoskeletal proteins in the zebrafish (Danio rerio) muscle development 2001
A miofibrilogênese no peixe-zebra (Danio rerio). 2001
Effects of EGTA in skeletal muscle cells in culture 2001
Muscle cytoskeletal proteins in the zebrafish Danio rerio 2000
Características particulares da diferenciação muscular e de proteínas do citoesqueleto em peixe-zebra (Danio rerio) 2000
EGTA induz alterações na forma celular e no citoesqueleto de células de músculo esquelético de camundongo crescidas em cultura 2000
Expressão de proteínas do citoesqueleto em Danio rerio 1999
Reformulação e ampliação do Banco de Imagens na internet do Laboratório de Imagem Biológica 1999
Associação entre desmina e membrana nuclear 1998
Inovações tecnológicas no ensino de histologia - uma avaliação 1998
Proteínas do Citoesqueleto e Organelas de Euglena Gracilis 1997
Laboratório de Imagem Biológica 1997
Avaliacao Videofluoroscopica e Quantificacao Computacional do Esvaziamento Gastrico 1996
Utilizacao da Computacao Na Imagem Biologica 1995
Estudo de Imunofluorescencia de Proteinas do Citoesqueleto de Organelas de Euglena Gracilis 1995
Estudo Imunocitoquimico dos Efeitos do Hormonio Tireoideano T3 Sobre O Citoesqueleto de Celulas Gliais 1994
Unidade de Aquisicao e Processamento de Imagem Biologica 1994
Trypanosoma Cruzi Cytoskeleton: An Imunofluorescence Study 1992
Myofibrilar Breakdown During Trypanosoma Cruzi Interaction With Heart Muscle Cells 1992
Myod Converts Non-Muscle Cells Into Striated Mononucleated Myoblasts And Multinucleated Myotubes 1991
Visualization Of Sputter Coated Detergent Extracted Heart Muscle Cellsby Scanning And Transmission Electron Microscopy 1991
Efeitos do Gene Diferenciador Myod1 Em Culturas Primarias de Celulas de Embriao de Galinha 1991
Padroes de Expressao de Isodesminas Especificos Para Cada Orgao Ele- Trico do Electrophorus Electricus, L. 1989
Cytoskeletal Proteins Of Normal And T Cruzi Infected Heart Muscle Cells 1988
Isodesmin Pattern In Some Special Physiological Conditions 1988
Desmin Expression In Dystrophic Muscle 1988
Differences In Desmin Isoforms Pattern Between Electric And Muscular Tissues 1987
The Desmin Isoforms In The Electric Eel 1986
Desmin In The Electric Organs Of Telectrophorus Electricus, L. 1985
Publicações:
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