Mauro Eduardo Weyne Ferreira da Costa

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biomembranas/Biof

ORCID:

não disponível no Lattes


Formação:

  • Australian Regenerative Medicine Institute, Monash University

    | Pós-Doutorado | 2011 - Agora

  • University of Toronto

    | Pós-Doutorado | 2010 - 2011

  • The Victor Chang Cardiac Research Institute

    | Pós-Doutorado | 2004 - 2007

  • The Victor Chang Cardiac Research Institute

    | Pós-Doutorado | 2001 - 2002

  • Albert Einstein College of Medicine

    | Pós-Doutorado | 1996 - 1997

  • Departamento de Genética

    Ciências Biológicas (Genética) | Doutorado | 1991 - 1996

  • Departamento de Genética

    Ciências Biológicas (Genética) | Mestrado | 1988 - 1991

  • Departamento de Genética

    Biologia | Graduação | 1984 - 1988
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(81.48% artigos com DOI)

Titulo DOI Ano
A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels 10.1016/j.diff.2015.12.003 2016
DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ 10.1159/000379749 2015
VISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery 10.1186/s12859-015-0578-0 2015
CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts 10.1371/journal.pone.0143274 2015
Microarray profiling to analyse adult cardiac fibroblast identity 10.1016/j.gdata.2014.10.006 2014
Cardiogenic Genes Expressed in Cardiac Fibroblasts Contribute to Heart Development and Repair 10.1161/CIRCRESAHA.114.302530 2014
Effect of Oxygen on Cardiac Differentiation in Mouse iPS Cells: Role of Hypoxia Inducible Factor-1 and Wnt/Beta-Catenin Signaling 10.1371/journal.pone.0080280 2013
Functional Characterization of a Novel Mutation in NKX2-5 Associated With Congenital Heart Disease and Adult-Onset Cardiomyopathy 10.1161/CIRCGENETICS.113.000057 2013
Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy 10.1038/ncomms2657 2013
Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases 2012
Complex SUMO-1 Regulation of Cardiac Transcription Factor Nkx2-5 10.1371/journal.pone.0024812 2011
Mutations in 357 Unrelated Patients with Congenital Heart Malformation 10.1089/gtmb.2010.0028 2010
Molecular Analysis of PRKAG2, LAMP2 and NKX2-5 Genes in a Cohort of 125 Patients with accessory atrioventricular connection 10.1002/ajmg.a.32907 2009
Conformational Stability and DNA Binding Specificity of the Cardiac T-Box Transcription Factor Tbx20 10.1016/j.jmb.2009.04.056 2009
BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4 10.1101/gad.1682108 2008
Mutations in Cardiac T-Box Factor Gene TBX20 Are Associated with Diverse Cardiac Pathologies, Including Defects of Septation and Valvulogenesis and Cardiomyopathy 10.1086/519530 2007
A tyrosine-rich domain within homeodomain transcription factor Nkx2-5 is an essential element in the early cardiac transcriptional regulatory machinery 10.1242/dev.02305 2006
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation 10.1242/dev.01799 2005
Transcriptional regulation of the murine promoter by cardiac factors Nkx2-5, GATA4 and Tbx5 10.1016/j.cardiores.2004.09.021 2004
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart 10.1016/S0012-1606(03)00385-3 2003
Homeodomain Factor Nkx2-5 in Heart Development and Disease 10.1101/sqb.2002.67.107 2002
Voltage dependence of macroscopic and unitary currents of gap junction channels formed by mouse connexin50 expressed in rat neuroblastoma cells 10.1111/j.1469-7793.1999.0673s.x 1999
Biophysical Properties of Lens Gap Junction Channels in Stably Transfected N2A Cells 1998
Identification of an Sp1-like Element within the Immunoglobulin ? 3` Enhancer Necessary for Maximal Enhancer Activity 10.1021/bi952801y 1996
Molecular Cloning and Sequence Analysis of a Segment from Andean Potato Mottle Virus B-RNA Encoding the Putative RNA Polymerase 1993
Complete Nucleotide Sequence of the 22 KDa Coat Protein of APMV 1992
Molecular Cloning and Analysis of the Andean Potato Mottle Virus 1989
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
25. CARDIAC TRASNCRIPTION FACTOR NKX2-5 IS REGULATED BY A COMPLEX SUMOYLATION PATTERN AND PROTEIN INTERACTIONS MEDIATED BY ITS CARBOXI-TERMINAL DOMAIN. 2010
BALANCING LEFT-RIGHT SIGNALING:HOW SMADS COMPETE FOR ACTIVATION OF TARGET GENES. 2010
HUMAN DUOX 2 PROMOTER ACTIVITY REGULATION BY HORMONES AND TRANSCRIPTION 2009
TRANSCRIPTIONAL ACTIVITY OF THE CARDIAC FACTOR NKX2-5 IS REGULATED BY SUMOYLATION 2008
FUNCTIONAL ANALYSIS OF A NOVEL NKX2-5 MUTATION UNRAVELS A POSSIBLE ROLE FOR THE UBIQUITIN-PROTEASOME SYSTEM IN CARDIOMYOPATHIES 2007
THE T-BOX TRANSCRIPTIONAL FACTOR TBX20 IS ESSENTIAL FOR CARDIAC AND VASCULAR DEVELOPMENT IN MICE. 2005
THE T-BOX TRANSCRIPTIONAL FACTOR TBX20 IS ESSENTIAL FOR VASCULAR DEVELOPMENT IN MICE. 2005
T-BOX TRANSCRIPTIONAL FACTOR TBX20 IS AN IMPORTANT TRANSCRIPTIONAL REPRESSOR IN VIVO AND IS ESSENTIAL FOR MURINE EMBRYONIC HEART DEVELOPMENT. 2005
T-BOX TRANSCRIPTIONAL HIERARCHIES GOVERNING THE ESTABLISHMENT OF CHAMBER VERSUS NON-CHAMBER MUSCLE IN THE DEVELOPING MURINE HEART. 2005
THE T-BOX TRANSCRIPTION FACTOR TBX20 IS ESSENTIAL FOR DEVELOPMENT OF THE MOUSE EMBRYONIC HEART. 2004
CHARACTERIZATION OF THE TRANSCRIPTION PATHWAY THAT REGULATES CX40 SPECIFICATION BY MULTIPLE CARDIAC FACTOR INTERACTIONS. 2003
Modulação Cardiaca da expressão da Conexina 40 por beta-estradiol em cultura primária de células atriais de rato neonato 2003
Obtenção de camundongos transgenicos condicionais para o estudo do papel da autoimunudade na Doenca de Chagas 2003
CONNEXIN40 PROMOTER REGULATION: CARDIAC FACTORS NKX2.5 AND GATA4 ARE CAPABLE OF INTERACTION AND ACTIVATION MEDIATED BY THE MINIMAL PROMOTER. 2002
CONNEXIN40 IS A DIRECT TARGET OF TRANSCRIPTION FACTORS NKX2.5, GATA4 AND TBX20. 2002
Cloagem e análise funcional de uma nova região do promotor da conexina40 2000
Murine Cardiac Transplantation Model Used to Study Autoimmunity in Neonatal Lupus 1999
Characterization and Functional Analysis of the Regulatory Elements within the Connexin40 Promoter 1999
RT-PCR for Detection of Different Connexin mRNAs 1999
Padrão de Expressão de Conexinas em Células Epiteliais Tímicas 1998
Caracterização do Padrão de Expressão da Conexina 40 Durante o Desenvolvimento Cardíaco 1998
Caracterização de Proteínas Formadoras de Junções Comunicantes no Sistema Imune 1998
Voltage Dependent Gating, Ionic Selectivity and Single Channel Properties of Gap Junction Channels Formed by Lens Cx50 in Stably Transfected Mammalian Cells 1998
Voltage Dependent Gating, Ionic Selectivity and Single Channel Properties of Gap Junction Channels Formed by Lens Connexin 50 in Stably Transfected Mammalian Cells 1997
Padrão de Expressão de Proteínas Formadoras de Junções Comunicantes em Células Epiteliais Tímicas 1997
Identification of an Sp1-Like Element within the Immunoglobulin k3' Enhancer Necessary for Maximal Enhancer Activity 1996
Evidence for the Role of GABPalfa and beta on the Transcription of the Cytochrome Oxidase Subunit Vb Gene 1996
Analysis of the Immunoglobulin Kappa 3' Enhancer: Identification of a New Regulatory Element 1996
Construção de Vetores em Eucariotos Codificando as Conexinas 32 e 40 1996
Restriction Pattern and Nucleic Acid Sequence Variation in the Andean Potato Mottle Virus (APMV) 1992
Isolation and Cloning of the Andean Potato Motthe Virus Coat Protein Genes 1992
Preliminary Studies on Primary Strucure of the Bottom RNA of the Andean Potato Mottle Virus (APMV) 1991
Preliminary Studies on Primary Structure of the Middle RNA of the Andean Potato Mottle Virus (APMV) 1991
Preliminary studies on Primary Structure of the Middle RNA of the Andean Potato Mottle Virus (APMV) 1991
Antisense RNA: Studies for Obtention of Transgenic Plants Resistent to Andean Potato Mottle Virus (APMV) 1991
Construção de Vetores Agrobaterium tumefaciens para a Introdução de Informação Genética Estranha em Plantas 1988
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