Leandro Miranda Alves

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

PR-5 Pró-Reitoria de Extensão

Unidade:

PR-5 Pró-Reitoria de Extensão

Departamento:

Superintendência Formação Acadêmica da Extensão

e-mail:

leandro.alves@icb.ufrj.br

Linkedin:

Google Scholar:

ORCID:

https://orcid.org/0000-0001-7832-8717

Formação:

  • Max Planck Institute of Psychiatry

    | Pós-Doutorado | 2007 - 2008

  • Max Planck Institute of Psychiatry

    | Pós-Doutorado | 2005 - 2005

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Farmacologia e Química Medicinal) | Doutorado | 2001 - 2005

  • Fundação Oswaldo Cruz

    Biologia Celular e Molecular | Mestrado | 1998 - 2001

  • Fundação Oswaldo Cruz

    Farmacologia Geral | Aperfeiçoamento | 1997 - 1998

  • Universidade Federal do Rio de Janeiro

    Farmácia-Habilitação Farmacêutico | Graduação | 1993 - 1997
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(98.67% artigos com DOI)

Titulo DOI Ano
TSH Receptor Reduces Hemoglobin S Polymerization and Increases Deformability and Adhesion of Sickle Erythrocytes 10.1155/2024/7924015 2024
Single microcystin exposure impairs the hypothalamic-pituitary-gonadal axis at different levels in female rats 10.1016/j.mce.2024.112203 2024
Maternal exposure to tributyltin alters the breast milk, hormonal profile, and thyroid morphology of dams and induces sex-specific changes in neonate rat offspring. 10.1016/j.envpol.2024.123963 2024
Unraveling DEHP influence on hemoglobin S polymerization in sickle cell disease: Ex vivo, in vitro and in silico analysis 10.1016/j.tiv.2024.105832 2024
Subacute cadmium exposure changes different metabolic functions, leading to type 1 and 2 diabetes mellitus features in female rats 10.1002/tox.24306 2024
Bosentan Attenuates Sickle Cell Disease Erythrocyte HbS Polymerization and Impaired Deformability Induced by Endothelin-1 10.1139/cjpp-2022-0012 2023
Endocrine-disrupting chemicals and endocrine neoplasia: A forty-year systematic review 10.1016/j.envres.2022.114869 2023
Subacute and Low Dose of Tributyltin Exposure Leads to Brown Adipose Abnormalities in Male Rats 10.1016/j.toxlet.2023.01.003 2023
Generation of an Obese Diabetic Mouse Model upon Conditional Atrx Disruption 10.3390/cancers15113018 2023
Subacute high-refined carbohydrate diet leads to abnormal reproductive control of the hypothalamic-pituitary axis in female rats 10.1016/j.reprotox.2023.108410 2023
Environmental health and toxicology: Immunomodulation promoted by Endocrine Disrupting-Chemical Tributyltin 10.3390/toxics11080696 2023
Environmental Endocrinology: Parabens Hazardous Effects on Hypothalamic–Pituitary–Thyroid Axis 10.3390/ijms242015246 2023
EVALUATION OF THE EFFECTS PRODUCED BY SUBACUTE TRIBUTYLTIN ADMINISTRATION ON VASCULAR REACTIVITY OF MALE WISTAR RATS 10.1016/j.tox.2021.153067 2022
Importância dos congressos estudantis para a formação médica: Uma experiência pioneira na Universidade Federal do Rio de Janeiro 10.18378/rebes.v11i4.8632 2022
Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner 10.1016/j.cbpc.2022.109279 2022
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes 10.1007/s12013-022-01096-y 2022
Connexin Expression in Pituitary Adenomas and the Effects of Overexpression of Connexin 43 in Pituitary Tumor Cell Lines 10.3390/genes13040674 2022
Environmentally relevant dose of the endocrine disruptor tributyltin disturbs redox balance in female thyroid gland 10.1016/j.mce.2022.111689 2022
Aggressive nonfunctioning pituitary neuroendocrine tumors 10.1007/s10014-022-00441-6 2022
Desenvolvimento de revistas didáticas como estratégia lúdica para o ensino da Morfofisiologia do sistema endócrino 10.16923/reb.v20i1.944 2022
Characterisation of an Atrx conditional knockout mouse model: Atrx loss causes endocrine dysfunction rather than pancreatic neuroendocrine tumour 10.3390/cancers1416386 2022
High-refined carbohydrate diet alters different metabolic functions in female rats 10.1016/j.mce.2022.111774 2022
Comparison between aerobic exercise training and enalapril treatment as tools to improve diet-induced metabolic-associated fatty liver disease: Effects on endoplasmic reticulum stress markers 10.1016/j.lfs.2022.121136 2022
Ouabain Effects on Human Anaplastic Thyroid Carcinoma 8505C Cells 10.3390/cancers14246168 2022
Atypical antipsychotics olanzapine and clozapine increase bone loss in female rats with experimental periodontitis 10.1111/jre.13090 2022
Effects of TSH in Erythrocyte Osmotic Fragility: Signalling Pathway 10.23937/2469-5696/1410048 2021
In vitro antitumoral effects of the steroid ouabain on human carcinoma cell lines 10.1002/tox.23130 2021
Cryopreserved Rat Thyroid Autotransplantation in the Treatment of Postoperative Hypothyroidism 10.3389/fendo.2021.625173 2021
Hypothyroidism induces oxidative stress and DNA damage in breast 10.1530/ERC-21-0010 2021
Signaling Pathway in the Osmotic Resistance Induced by Angiotensin II AT2 Receptor Activation in Human Erythrocytes 10.52547/rbmb.10.2.314 2021
Tributyltin and high¿refined carbohydrate diet lead to metabolic and reproductive abnormalities, exacerbating premature ovary failure features in the female rats 10.1016/j.reprotox.2021.06.004 2021
Relevant dose of the environmental contaminant, tributyltin, promotes histomorphological changes in the thyroid gland of male rats 10.1016/j.mce.2019.110677 2020
Dietary zinc restriction promotes degeneration of the endocrine pancreas in mice 10.1016/j.bbadis.2020.165675 2020
Disruption of fertility, placenta, pregnancy outcome, and multigenerational inheritance of hepatic steatosis by organotin exposure from contaminated seafood in rats 10.1016/j.scitotenv.2020.138000 2020
High¿refined carbohydrate diet leads to polycystic ovary syndrome-like features and reduced ovarian reserve in female rats 10.1016/j.toxlet.2020.07.002 2020
The impact of endocrine-disrupting chemical exposure in the mammalian hypothalamic-pituitary axis 10.1016/j.mce.2020.110997 2020
Subacute Exposure to Lead Promotes Disruption in the Thyroid Gland Function in Male and Female Rats 10.1016/j.envpol.2020.115889 2020
Effects of Bisphenol A and S on blood coagulation: in vivo , in vitro and in silico approaches in toxicodynamic 10.1080/15376516.2020.1836102 2020
Brown adipose tissue remodeling induced by corticosterone in Wistar male rats 10.1113/ep087332 2019
The Tributyltin Leads to Obesogenic Mammary Gland Abnormalities in Adult Female Rats 10.1016/j.toxlet.2019.02.016 2019
Differential Expression of HMGA1 and HMGA2 in pituitary neuroendocrine tumors 10.1016/j.mce.2019.04.010 2019
Inhibition of Type 1 Iodothyronine Deiodinase by Bisphenol A 10.1055/a-0919-3879 2019
The Pollutant Organotins Leads to Respiratory Disease by Inflammation: A Mini-Review 10.3389/fendo.2017.00369 2018
Tributyltin and Zebrafish: Swimming in Dangerous Water 10.3389/fendo.2018.00152 2018
Rutin Scavenges Reactive Oxygen Species, Inactivates 5--Adenosine Monophosphate-Activated Protein Kinase, and Increases Sodium-Iodide Symporter Expression in Thyroid PCCL3 Cells 10.1089/thy.2016.0585 2018
The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats 10.1016/j.envpol.2018.06.006 2018
Unraveling molecular targets of bisphenol A and S in the thyroid gland 10.1007/s11356-018-2419-y 2018
The Obesogen Tributyltin Induces Abnormal Ovarian Adipogenesis in Adult Female Rats 10.1016/j.toxlet.2018.06.1068 2018
Bisphenol A increases hydrogen peroxide generation by thyrocytes both in vivo and in vitro 10.1530/ec-18-0348 2018
Environmental obesogen tributyltin chloride leads to abnormal hypothalamic-pituitary-gonadal axis function by disruption in kisspeptin/leptin signaling in female rats 10.1016/j.taap.2017.01.021 2017
Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer 10.1007/s12672-017-0307-4 2017
Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis 10.1016/j.mce.2017.07.038 2017
Tributyltin chloride induces renal dysfunction by inflammation and oxidative stress in female rats 10.1016/j.toxlet.2016.08.007 2016
The Environmental Pollutant Tributyltin Chloride Disrupts the Hypothalamic-Pituitary-Adrenal Axis at Different Levels in Female Rats 10.1210/en.2015-1896 2016
TIMP-2 gene methylation in cervical precursor and invasive lesions 10.1016/j.yexmp.2015.01.008 2015
Tributyltin chloride leads to adiposity and impairs metabolic functions in the rat liver and pancreas 10.1016/j.toxlet.2015.03.009 2015
Accumulation of organotins in seafood leads to reproductive tract abnormalities in female rats 10.1016/j.reprotox.2015.05.003 2015
Influence of Organotin on Thyroid Morphophysiological Status 10.15436/2378-6841.15.018 2015
The reciprocal interactions between astrocytes and prostate cancer cells represent an early event associated with brain metastasis 10.1007/s10585-014-9640-y 2014
Hypothalamic-pituitary thyroid axis alterations in female mice with deletion of the neuromedin B receptor gene 10.1016/j.regpep.2014.10.002 2014
Low somatostatin receptor subtype 2, but not dopamine receptor subtype 2 expression predicts the lack of biochemical response of somatotropinomas to treatment with somatostatin analogs 10.3275/8305 2013
Sexual Dimorphism of Thyroid Reactive Oxygen Species Production Due to Higher NADPH Oxidase 4 Expression in Female Thyroid Glands 10.1089/thy.2012.0142 2013
Lycopene and Beta-Carotene Induce Growth Inhibition and Proapoptotic Effects on ACTH-Secreting Pituitary Adenoma Cells 10.1371/journal.pone.0062773 2013
The follicular thyroid cell line PCCL3 responds differently to laminin and to polylaminin, a polymer of laminin assembled in acidic pH 10.1016/j.mce.2013.05.020 2013
Validation of immunohistochemistry for somatostatin receptor subtype 2A in human somatotropinomas: comparison between quantitative real time RT-PCR and immunohistochemistry 10.3275/7906 2012
Extracellular matrix secreted by reactive stroma is a main inducer of pro-tumorigenic features on LNCaP prostate cancer cells 10.1016/j.canlet.2012.02.026 2012
Role of Estrogen and Progesterone in the Modulation of CNG-A1 and Na + /K + -ATPase Expression in the Renal Cortex 10.1159/000339055 2012
Tributyltin Impairs the Coronary Vasodilation Induced by 17β-Estradiol in Isolated Rat Heart 10.1080/15287394.2012.695231 2012
Estradiol modulates TGF-β1 expression and its signaling pathway in thyroid stromal cells 10.1016/j.mce.2011.02.001 2011
Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia 10.1016/j.jep.2011.03.003 2011
A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model 10.1016/j.fertnstert.2009.11.037 2010
Bone marrow subendosteal microenvironment harbours functionally distinct haemosupportive stromal cell populations 10.1007/s00441-004-1006-3 2005
A continuous lineage of rat adenohypophysis stromal cells: characterisation and effects on GH3B6 prolactin-secreting cell behaviour 10.1016/s0248-4900(02)00020-5 2002
Mechanism of the Hypotensive Action of Rhazya stricta Leaf Extract in Rats. 2000
Pyridostigmine blunts the increases in myocardial oxygen demand elicited by the stimulation of the central nervous system in anesthetized rats 10.1007/bf02311764 1999
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Carotenoids inhibits cell proliferation, arrest cell cycle and induces apoptosis in pituitary tumor cells 2011
Connexins Expression and Gap Junction Communication Analysis in Adenohypophysis Cell Lines 2008
Can estrogen induce in vitro TGF-beta1 signal from stromal cells to follicular thyroid cells? 2008
Artificial laminin polymers assembled in acid pH affect PCCL3 epithelial thyroid cell morphology and activity 2008
Efeitos do ácido retinóico e análise da expressão dos receptores RAR e RXR em células tireoideas normais PCCL3 2007
O extrato hexânico do babaçu inibe a proliferação das células tumorais AtT-20 2007
Bone marrow mononuclear cells attenuated collagen deposition and modulates inflammatory response in lung murine fibrosis 2007
Estrogen modulates TGFbeta1 and TGFRII expression but not the TGFbeta1 signaling pathway in thyroid stromal cells 2006
Estrogênio protege as células tireoideas (PCCL3) da morte celular promovida por H2O2 2005
Estrogênio protege células tireoideanas (PCCL3) da morte celular promovida por peróxido de hidrogênio 2005
Estrogen Protects PCCL3 Thyroid Cells Against Death Induced by Hydrogen Peroxide 2005
Thyroid stromal cells modulate FRTL5 epithelial cells activity 2004
Structure of Laminin Substrate Modulates FRTL5 Epithelial Thyroid Cells Behaviour 2004
Role of gama-IFN on Pulmonary Fibrosis Elicited by Experimental Silicosis 2004
Mycophenolate Mofetil Attenuates Renal Injury And Fibrosis In Unilateral Obstruction Rats 2004
Estrogênio modula a proliferação de células tireoideanas (FRTL5) na presença de tireotrofina 2004
Intestinal Muscularis Mucosa And Myenteric Plexus Hyperplasia In Crohn´s Disease 2004
Efeito de Diferentes Concentrações de Interferon Alfa e Ribaverina sobre Osteoblastos Humanos 2003
Isolation and characterisation of rat gastric mucosa stromal cells culture 2002
Estabelecimento e Carcterização de células pancreáticas e de medula óssea murinas para obtenção de células secretoras de insulina: Estudos preliminares 2002
Thyroid stromal cells can modulate in vitro thyroglobulin secreting FRTL5 cells behaviour 2002
Establishment and characterization of human endometrial stromal cells culture 2002
In vitro expression of extracellular matrix components, MMP-3, MMP-7, TIMP-1,TIMP-2, and gastrin in human gastric mucosa 2002
Analysis of extracellular matrix molecules expressed by two distinct subendoteal stromal cells 2002
Estabelecimento e carcaterização de uma linhagem homogênea de células estromais tireoideanas 2002
Stromal cells from primary culture of rat thyroid gland:Initial isolation and characteriztion 2002
Expressão in vitro de elementos de matriz extracelular em mucosa gástrica humana 2002
Interação entre as células GH3B6 secretoras de prolactina e células estromais de adenohipófise 2002
Caracterização do Estroma Adenohipofisário de Rato e seus Efeitos sobre a Distribuição de Prolactina em Células da Linhagem Tumoral GH3B6. 2000
STROMAL CELLS OF THE RAT ANTERIOR PITUITARY: CHARACTERIZATION AND EFFECTS ON PROLACTIN SECRETION. 2000
Isolation, characterization and establishment of rat anterior pituitary stromal cell culture 2000
A Continuous Lineage of Adenohypophyse Stromal Cells: Characterization and Effects on Prolactin Secretion 2000
Efeitos Cardiovasculares Centrais do Extrato de Rhazya stricta em Ratos Anestesiados. 1999
Stromal cells of the Rat Anterior Pituitary: Characterization and Effects on Prolactin Secretion 1999
Efeitos Cardiovasculares Centrais da Fração Alcaloídica de Rhazya stricta em Ratos Anestesiados 1999
A Piridostigmina Inibe os Aumentos de Consumo de Oxigênio pelo Miocárdio Induzidos pela Estimulação Central em Ratos Anestesiados 1998
Investigação das Alterações Hemodinâmicas Secundárias à Liberação de Endotoxina Bacteriana, por Antimicrobianos, em Ratos Anestesiados 1998
Pyridostigmine Blunts the Centrally-Evoked Increases in Myocardia Oxygen Demand in Anesthetized Rats.l 1998
Cardioproctective Action Elicited by the Inhibition of Acethylcholinesterase in Anesthetized Rats 1998
Cardioprotective Action Elicited by the Inhibition of Acethylcholinesterase in anaesthetized Rats 1998
Efeitos do Baclofen sobre o Aumento do Consumo de Oxigênio pelo Miocárdio Induzido Centralmente em Ratos Submetidos à Inibição Crônica da Síntese do Óxido Nítrico 1998
Variação dos Índices de Trabalho cardíaco e do Consumo de Oxigênio pelo Miocárdio Decorrentes da Estimulação Glutamatérgica do NPV em Ratos. 1997
Flavonóides de Croton Hemiargyreus MUELL ARG. 1995
Estudo Fitoquímico de Croton echinocarpus MUELL ARG. 1995
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