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aedes aegypti fibrosis patient burkholderia kururiensis pacientes biosurfactant burkholderia cepacia xylose glioblastoma cell identificacao gene cystic fibrosis bacteria molecular casein kinase epithelial escherichia coli genoma rhamnolipid production burkholderia protein cenocepacia enteropathogenic escherichia mosquito blood sucking salivary gland rhodnius prolixus