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allergic asthma celula group streptococcus extracellular human endothelial derived mononuclear aerobic exercise cigarette smoke acute lung migration infection host cell growth hormone phytomonas serpens chronic mesenchymal stromal murine lung injury protease copd bone marrow pseudallescheria boydii lung group streptococci interaction diesel exhaust thymic tritrichomonas foetus endothelial cells candida albicans