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host cell lung injury cell induced group streptococcus triiodothyronine trypanosoma cruzi group streptococci candida albicans celula phytomonas serpens tritrichomonas foetus thymic epithelial stromal cell toxoplasma gondii trypanosomatid lung characterization aerobic exercise desenvolvimento deteccao pulmonary atividade mice mucociliary clearance marrow derived activation receptor diesel exhaust migration